Hello Claudenir Fonseca,
Thank you for publishing in Microsoft Community. We are happy to help you.
I'm sorry to hear that you're experiencing issues with "Cmd + Backspace" stopped working on the web version of Outlook.
Please can i you confirm with you if you are talking about of "Cmd + Delete" Reference: Keyboard shortcuts for Outlook - Microsoft Support.
However, after try the above shortcut from my end it is working, in Edge and chrome. This shortcut cmd + Delete is for Delete "Delete the character to the left of the cursor or delete the selected text." or "Delete the character to the right side of the cursor or delete the selected text." And Option+ Delete is to delete the last word.
However, to better understand the issue and we need more details from you, please kindly provide us the following information. Thank you.
1-Please kindly let me know what happen when you use shortcut cmd + Delete?
2-Please may i know the type of the keyboard you are using since you are talking about Cmd+Backspace instead Cmd+Delete
3-Is it possible to use the same shortcut in different device and let me know the issue
Note: "Opt + Shift + Arrow keys" This is a universal key command on a Mac that just stopped working with Outlook and Outlook only. After check we Mac support thread the team are aware about the issue and the outlook for Mac, recently some universal key not working and the dedicate team are working on it.
We look forward to your reply. This requested information will help us narrow down the scenario and find the right troubleshooting. We will continue to assist you based on the information you provide. I sincerely appreciate your patience and cooperation.
Eben Ezer Tres | Microsoft Community Moderator