Thanks for reaching out to us here on the Forums!
We understand this can be frustrating since the Mouse is not recognized when trying to maneuver Microsoft Edge on
the Xbox One. We have heard there are issues with using the mouse on Microsoft Edge but the keyboard works. We are gathering information on this issue.
Note: Wired USB mice will work only
in select games and apps that have enabled mouse navigation. Check your games to see if they offer mouse input.
Try to
configure your mouse in Settings > Kinect & devices.There are options
for pointer speed and swapping primary and secondary mouse buttons.
I hope this helps. Thank you