Last night was playing the campaign with the Machinations deck. Got to a point where I had a lot of big guys out and it was clear I was going to win, so I decided to see how lopsided I could get. It got down to where I had almost every creature in the deck on the board and a lot of tokens, they were all tokened up with many many +1/+1. I attacked on my last possible turn (no cards left in the library) and the game ended with a score of 784 to -1208.
What's the most lopsided win you've ever had?