As of tonight, July 30 2015, my Xbox 360 updated to new system update (2.0.17449.0).
When launching Gears of War 2, it will play both Epic Games logo animation and Microsoft game's logo animation before black screening and system will lock up.
I have tried multiple times relaunching the game with the same results. I also cleaned disk and no changes.
I was playing this game two nights ago, July 28, with no issues.
If anyone else is having this issue, please do tell.