Yes, but you have to format it using your xbox. I did the same thing on a 15 gig SSD(using a sata to usb enclosure) that I re-purposed from a lap top upgrade. I formatted for the minimum xbox storage(256mb) so I could use it as a music drive. I suppose
you would format for maximum xbox storage. Check the Xbox 101- hardware area of the community tab and view USB storage.
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