Unable to uninstall several programs from the Control Panel. Error 1327: Invalid Drive.

Using "Add/Remove Programs" in the Control Panel, I am trying to uninstall several programs from my laptop and each one gets the massage "Error 1327.Invalid Drive E:\. I click "OK" and receive another message: "Fatal error during installation".

My laptop was connected to a network and I used an exterior drive for backing up; no longer connected to either but could be. 
original title: Error 1327. Invalid Drive: E:\__

Question Info

Last updated April 12, 2019 Views 42,596 Applies to:
Hi Tuxedocat,

Thanks for posting. Please try the following.

Hit Start, Run and type Regedit

Find the following HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\ Explorer\User Shell Folders

In the right pane - see if there are  any entries which has an F or any other letters besides C (your OS folder) modify data to C:\

Modifying REGISTRY settings incorrectly can cause serious problems that may prevent your computer from booting properly. Microsoft cannot guarantee that any problems resulting from the configuring of REGISTRY settings can be solved. Modifications of these settings are at your own risk.

Hope this helps!

Shawn - Support Engineer - MCP, MCDST
Microsoft Answers Support Engineer
Visit our Microsoft Answers Feedback Forum and let us know what you think

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