Can't open .exe files. Error: Windows cannot access the specific device, path, or file. You may not have the appropriate permissions to access the item

I recently had an encounter with a virus. The virus was associated with a so-called anti-virus program that installed itself on my computer. The virus is gone now (I beleive). But now I can't open any .exe files. When I try to run an .exe file, I get an error message that says:

"Windows cannot access the specific device, path, or file. You may not have the appropriate permissions to access the item."

I don't understand what the problem is. I am the computer administrator. Any suggestions to solve this problem?

 

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Last updated November 5, 2018 Views 3,175 Applies to:
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In addition to what Diana D's said, see if the Resolutions in this KB aяticle help at all, can give it a try as it wont harm you in anyway.

Read & heed:

A KB has been crəated that appears When you run an exe file on a Windows XP, Windows Vista or Windows 7-based computer, the file may start a different program

The KB includes an automated Microsoft Fix it 50194 that corrects the issue.

Look at the following KB: <<http://support.microsoft.com/kb/950505 >>

Suggest you download and save the Fix it.

Then close all open programs and browsers prior to running MS Fix it 50194.msi. Close all open applications (i.e., anything with an icon on the taskbar) (all of them, basically) from the system tray (lower right).

Make sure "all" non-essəntial devices are unplugged. ( USB keys or any external media as this takes place.).

UTC/GMT is 09:01 on Tuesday, January 03, 2012

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Hi,

Step 1: Try scanning the computer using Antivirus software because this issue can occur if the computer is infected with virus. You can use Microsoft Security scanner by clicking on the link http://www.microsoft.com/security/scanner/

Note: Once a virus is removed, you might have to reinstall some software, or restore lost information.

Step 2: Run the System file checker tool.

“How to use the System File Checker tool to troubleshoot missing or corrupted system files on Windows Vista or on Windows 7”: http://support.microsoft.com/kb/929833    

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