Try a System Restore to before the problem.
"Using Windows 7 or Vista System Restore"
Read this Microsoft information and use their Mr. Fixit
"Fix broken desktop shortcuts and common system maintenance tasks"
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The desktop icons have gone white and do not work as shortcuts. Right click on the desktop does nothing.
Try rebuild your icon cache. It could be corrupted.
Also, you might want to see if there is corruption in some of your system files.
Use this tutorial to do system file check. It will try to do repair if any found.