I have Win 7 x64 running on an MSI G41-M7 mobo, E2220 processor, 500G HDD, 4G RAM. It was running great until 4 days ago (11.04.24) when I shut it down in the PM. It installed a patch at that time. When I booted next morning, it worked for a while (5 minutes or so), then the mouse and keyboard were locked out, while the HDD was chattering away. I needed to use the machine, so I killed the power (mistake) and rebooted in safe mode. It did the same thing there (froze after a few minutes), and after a half hour it rebooted, but didn't find the boot drive. After powering down, I managed to get it to boot to safe mode and did a system restore to the pre-update state. After this, it booted fine normally, and I was able to use it all day. Then, on powering down, it installed an update (presumably the one I restored from), shut itself down, and I have not been able to boot it since. It'll start to boot, sit there with the little whirling donut for 20 or so minutes, attempt a re-boot, and won't find the boot drive. Startup repair gives the above message, even when run from the installation disk.