Hi Joe. I'm Greg, an installation specialist, 10 year Windows MVP, and Volunteer Guardian Moderator here to help you.
What player is it using for Amazon Prime? If it's a web player then try another browser. Make sure the browser's Flash is enabled and current by running this tool:
https://helpx.adobe.com/flash-player.html
For Edge use these extra steps:
https://www.digitalcitizen.life/how-unblock-fla...
If necessaary reset the browser as shown here:
https://www.howtogeek.com/171924/how-to-reset-y...
If this is Windows Media Player Download and run this WMP troubleshooter from Microsoft:
http://aka.ms/diag_wmpc10
You may need to install WMP from Settings > Apps > Apps & Features > Optional Feature > Add a Feature, add WMP here.
Other WMP troubleshooting fixes that have worked recently here:
https://www.thewindowsclub.com/windows-media-pl...
https://www.lifewire.com/troubleshooting-tips-f...
https://www.kapilarya.com/fix-problems-with-win...
https://appuals.com/fix-windows-media-player-ha...
https://www.howtogeek.com/howto/26107/how-to-re...
http://m.majorgeeks.com/content/page/how_to_tro...
https://www.thewindowsclub.com/troubleshooting-...
Try reinstalling Windows Media Player: Type Features in Start Search, open Turn Windows Features On or Off, under Media Features, uncheck Windows Media Player, click OK. Restart PC, then reverse the process to check WMP, OK, restart again to reinstall it.
If it's not present then type Features in search box, choose Manage Optional Features, then if not in list to those to add choose Add a Feature to add it.
Try VLC Media Player from here:
http://www.videolan.org/vlc/index.html
Try Movies & TV app which comes built-in Windows 10.
I hope this helps. Feel free to ask back any questions and let us know how it goes. I will keep working with you until it's resolved.
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Standard Disclaimer: There are links to non-Microsoft websites. The pages appear to be providing accurate, safe information. Watch out for ads on the sites that may advertise products frequently classified as a PUP (Potentially Unwanted Products). Thoroughly research any product advertised on the sites before you decide to download and install it.