This may also occur due to user account corruption:
I would suggest you to go through the below methods:
Method 1: Try to perform clean boot:
A clean boot is performed to start Windows by using a minimal set of drivers and startup programs. This helps eliminate software conflicts that occur when you install a program or an update or when you run a program in Windows 8.1, Windows 8, Windows 7,
or Windows Vista. You may also troubleshoot or determine what conflict is causing the problem by performing a clean boot.
Note: Refer "How to reset the computer to start normally after clean boot troubleshooting" to reset the computer to start as normal after troubleshooting.
Method 2: Try to add custom exclusions in addition to the ones automatically added, start a Windows PowerShell console as an administrator, and run the following command:
On the start screen, type power shell, right click on it and select run as admin.
Add-MpPreference -ExclusionPath "c:\temp"
To remove exclusions, start a Windows PowerShell console as an administrator, and run the following command:
Remove-MpPreference -ExclusionPath "c:\temp"
Also refer the link below:
How to exclude a file/folder from Windows Defender malware scan in Windows 8/8.1?