I have a client that relies heavily on indexing to search her 7GB email file. I have already tried the following:
1) Delete email profile and created a new one.
2) Repair installion of Office 2010.
3) Repaired Inbox using "Inbox Repair Tool".
4) Compacted Inbox (from 9.5GB down to 7.4GB).
5) Rebuilt Indexes and allowed an entire weekend for indexing to complete ... but it never does.
There are a ton of hits on Google about this very problem, but I have yet to find a successful answer.
She is running Windows 7 (64-bit) with Office 2010 (32-bit).