Outlook 2016 Will Not Open error: Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened

I've upgraded to WIN 10 and also upgraded to Office 365/2016.

Outlook 2016 will not open with this configuration.

Error message: "Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened".

I also cannot start Outlook in safe mode to check add-ons from previous version 365/213.

I note from reading various posts that sometimes Evernote can cause issues, but have also not had problem with Evernote and Office 365/2013.

Appreciate any advice that may be available to resolve the issue.

[Original Title: Outlook 2016 Will Not Open]

 

Question Info


Last updated September 25, 2018 Views 373,860 Applies to:
Answer

THIS WORKED!  However I did it slightly different:

1. Right click the Windows button, select Control Panel

2. Select Mail (Microsoft Outlook 2016) (32-bit)

3. Click Show Profiles

4. Remove the existing Profile (ALL PROFILES!)

5. Close Window

6. Start Outlook

7. Create a new Profile

CHEERS!

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Answer

Hi Neil,

Thank you for posting your query in Microsoft Office Community.

Refer to the following article and check if it helps.

I can’t start Microsoft Outlook 2010 or 2013 or receive the error “Cannot start Microsoft Office Outlook. Cannot open the Outlook Window” 

 https://support.office.com/en-us/article/I-can-t-start-Microsoft-Outlook-2010-or-2013-or-receive-the-error-Cannot-start-Microsoft-Office-Outlook-Cannot-open-the-Outlook-Window-d1f69da6-b333-4650-97bf-4d77bd7abb85?CTT=1&CorrelationId=20910bad-e0d8-4bcd-aa2a-a0859c222018&ui=en-US&rs=en-US&ad=US

Note: Also applicable to Office 2016.

Hope the above information helps. Reply if you need more assistance and I'll be happy to help you.

Thank you.

206 people were helped by this reply

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