Note : Please note that running Reset Internet Explorer Settings will reset all user-defined settings including those set by installed extensions, toolbars and other add-ons to IE Defaults. This includes all Security, Privacy and Zone settings.
Also this will clear browsing history, delete all temporary Internet Files, cookies, form data and especially all stored passwords.
Check if the issue exists in safe mode with networking.
You can try starting your computer in Safe mode with networking and see if it works fine.
A description of the Safe Mode Boot options in Windows XP