Let us know if the issue does not persist in ‘Safe Mode with Networking’, we shall proceed with further troubleshooting Method 2: You may run Internet Explorer in "No Add-Ons" mode and check if you are able to open up links.
Follow the steps mentioned below.
Run Internet Explorer in "No Add-Ons" mode
1.Click Start, and then type Internet Explorer in the Start Search box.
2.Click Internet Explorer (No Add-Ons). Internet Explorer opens without add-ons, toolbars, or plug-ins.
3.Test Internet Explorer to verify that it works correctly. If it works then you can disable add-ons (follow step 2).
Use the Manage Add-ons tool to determine which add-on is causing the issue
1.Open Internet Explorer 8.
2.Click Tools, and then click Manage Add-ons.
3.On the Show drop-down menu, select All add-ons to display all add-ons that are installed on the computer.
4.For each item in this list, select the add-on, and then click Disable in the Information window.
5.When you have disabled all the items in this list, click OK. 6. Exit and then restart Internet Explorer.
7.If issues do not reoccur, repeat steps 1 through 3.
8.Click Enable for a single add-on.
9.Repeat steps 6 through 8 until you determine which add-on causes errors to occur.