Outlook 2016 Crashes when launch.

Same problem as mentioned without a solution.

Setup is Win 7 Ent 64 bits. Other than outlook 2016 other apps (PP/Excel/Word etc) work just fine.

Have another setup with Win 10, Outlook 2016 works just fine.

Crashinfo on Win 7

Problem signature:

  Problem Event Name: APPCRASH

  Application Name:         OUTLOOK.EXE

  Application Version:     16.0.4266.1003

  Application Timestamp:              55ceb248

  Fault Module Name:    AppVIsvSubsystems32.dll

  Fault Module Version: 5.0.10331.0

  Fault Module Timestamp:          55843043

  Exception Code:             c0000005

  Exception Offset:           0008a0ac

  OS Version:      6.1.7601.2.1.0.256.4

  Locale ID:           1033

Additional information about the problem:

  LCID:    1033

  skulcid:               1033

Been seeing the same problem here. We run McAfee AV, and figured out that if we temporarily disable Host IPS from the system tray, Outlook 2016 will launch just fine.

This workaround needs to be repeated after every reboot. We've got a ticket open with McAfee to try and find a permanent solution.

I also ran into this issue with McAfee SaaS. I went into the control panel and found it was the exploit prevention that was causing the issue. If you go into the advanced settings you can create an exception for Outlook.exe and then it will work.

Hope this helps some of you with this headache. Thanks to Chuck Vandenberg's post above that pointed me in the right direction. I didn't have the options he did but was able to resolve with the version of McAfee we were using.

Had exactly the same issue with Outlook failing to start at all after clean install of Office 365 (2016) on a clean install Win7 laptop. Mail settings in control panel also failed to function.

I called MS tech help who were pretty much no help at all.

I eventually narrowed it down to Mcafee AV preventing Otulook.exe running.

It apparently classes Outlook.exe as attempting to exploit my system.

In the Mcafee control panel I added Outlook.exe to list of Exclusions under the settings for "Exploit prevention" and had instant success with Outlook working normally.

I haven't had time to find out what process runs when trying to access mail settings in control panel (to add this as an exception also), but at the moment I'm just happy (!!) that Outlook is now working as it should.